Liposomes can be created by sonicating a dispersion of aphipatic lipids, such as phospholipids, in water. Phospholipids are organic compounds and a certain type of fats, i.e. lipids. They are crucial components of cell membranes of all living organisms. Phospholipids are characterised by amphiphilic properties. One tail of the phospholipid is hydrophobic (water-hating) and is not water-soluble, while the other is hydrophilic (water-loving), and thus is soluble in water. Due to such specific properties, the cell membrane tends to be selective in permeation, which means that certain molecules may not pass through the membrane and enter the cell.
The demand for liposomal herbs is triggered by low bioavailability and insufficient absorption of traditional medicines. Herbs covered with a liposomal layer are absorbed immediately by the lymphatic system in intestines, and not by the portal venous system which carries blood to the liver. Good quality liposomes allow the absorbed medicine to omit the liver, as opposed to antibiotics. Antibiotics (per os) enter the bloodstream usually through the portal venous system, due to which the whole dose of absorbed medicine passes through the liver first. Medicines are then exposed to the activity of liver enzymes and ultimately metabolized. The faster the metabolism works, the lower the bioavailability of a medicine appears to be.
Liposomes enter the lymphatic system on the intracellular level almost immediately. As study shows, spirochetes and bartonella mainly spread through the lymphatic system. By entering the infected lymphatic system, liposomal herbs are able to sequentially eliminate microbes. When liposomes reach the thoracic duct, they are absorbed into the bloodstream and dispersed.
Liposomes are known to have specific properties of crossing the blood-brain barrier, as opposed to antibiotics. In most cases, chronic Lyme disease, babesia or bartonella may affect the patient’s brain and result in brain fog, derealization and other neurological problems. Crossing the blood-brain barrier is usually highly difficult, and thus liposomal herbs are crucial in brain infections treatment.
Latest studies show that liposomal herbs effectively penetrate biofilm, which is most likely responsible for relapse occurring after antibiotic treatment. There is no effective antibiotic treatment that would tear down biofilm, which occurs as a consequence of chronic Lyme disease. This statement was confirmed by Eva Sapi at the ILADS Conference in June.
Currently, there are no approved methods of treating biofilm-related infections, including the Lyme disease. Alternative methods of treatment may, to some extent, relieve Lyme disease symptoms or even fight biofilm. According to the report of the National Center for Biotechnology Information (NCBI), liposomes are believed to be the new strategy of both preventing and treating biofilm-related infections, such as the Lyme disease. Nanoliposomes have remarkably large surfaces that are able to influence microorganisms better than antibiotics. They can penetrate through bacterial biofilm and react with proteins and DNA, breaking the bacteria’s respiratory chain and disrupting cell division. Consequently, the bacterial cell dies.
The combination of liposomes and antibiotics, supported by appropriate supplementation enables patients with chronic diseases to look optimistically to the future.