środa, Październik 17, 2018
Strona główna formuły liposomalne B&M NANOBAB

B&M NANOBAB

298.00

SKU: 603023 Kategoria: Tag:

Opis

B&M NANOBAB – liposomalna formuła ziołowa fitoterapeuty Jana Oruby

Zawartość netto: 100 ml
Suplement diety. Formuła liposomalna na bazie preparatów roślinnych.
Przeznaczony do stosowania jako uzupełnienie diety osób dorosłych w wybrane składniki roślinne.

Sposób użycia: 3 razy dziennie po max. 1 ml (20 kropli), spożywać z niewielką ilością wody, co najmniej 15 minut przed posiłkiem. Przed odmierzeniem porcji wstrząsnąć butelką.

Przechowywanie: W szczelnie zamkniętym opakowaniu, w chłodnym miejscu, w sposób niedostępny dla małych dzieci. Chronić przed światłem. Po otwarciu przechowywać w lodówce.

Składniki:

olejek z kłącza kurkumy (Curcuma longa),
olejek niaouli z liści (Melaleuca viridiflora),
olejek z liści trawy cytrynowej (Cymbopogon flexuosus),
olejek ylang ylang z kwiatów (Cananga odorata),
ekstrakt z propolisu (Kit pszczeli),
ekstrakt z kory korkowca amurskiego (Phellodendron amurense),
ekstrakt z kłącza ostryżu cytwarowego (Curcuma zedoaria),
ekstrakt z korzenia Cryptolepis buchanani,
ekstrakt z korzenia Dichroa febrifuga

Suplementy diety nie mogą być stosowane jako substytut zróżnicowanej diety. Nie przekraczać porcji zalecanej do spożycia w ciągu dnia. Produkt nie jest przeznaczony dla dzieci w wieku poniżej 12 lat oraz kobiet w ciąży i karmiących piersią.

Preparaty liposomalne ze względu na strukturę cząsteczki i swój skład najlepiej spożyć w przeciągu 3 miesięcy od daty produkcji.

Po tym okresie skład preparatu nie ulega pogorszeniu, ale jego bioprzyswajalność zaczyna maleć co może skutkować stopniowym spadkiem jego bioprzyswajalności.

Zioła liposomalne najlepiej stosować pod nadzorem specjalistów (lekarza, fitoterapeuty lub dietetyka) ukierunkowanych w problematyce boreliozy i koinfekcji.

Konieczna jest:

odpowiednio prowadzona dieta,
zdrowy tryb życia,
odpowiednio prowadzona detoksykacja organizmu.


Więcej informacji dotyczących problematyki chorób odkleszczowych uzyskać można na naszym portalu: www.akademia-boreliozy.pl

na blogu fitoterapeuty Pana Jana Oruby: https://fitoterapeuta.wordpress.com/
oraz u fitoterapeuty Pana Pawła Feknera – email: fitoterapeuta.pawel@interia.pl

 

flaga_GB

Description

B&M NANOBAB – liposomal herbal formula of the Jan Oruba phytotherapist

Net content: 100 ml
Diet supplement. Liposomal formula based on plant preparations.
Intended for use as an adult diet supplement in selected plant ingredients.

How to use: 3 times a day max. 1 ml (20 drops), consume with a small amount of water, at least 15 minutes before a meal. Before measuring the portions, shake the bottle.

Storage: In a tightly closed container, in a cool place, keep away from small children. Protect from light. After opening, store in a refrigerator.

Components:

turmeric root oil (Curcuma longa),
niaouli oil (Melaleuca viridiflora),
lemongrass oil (Cymbopogon flexuosus) oil,
ylangylang oil from flowers (Cananga odorata),
propolis extract (Bee’s Kit),
amber bark cortex extract (Phellodendron amurense),
extract of citrouscitrous rhizome (Curcuma zedoaria),
root extract Cryptolepis buchanani,
root extract Dichroa febrifuga

Dietary supplements cannot be used as a substitute for a varied diet. Do not exceed the portion recommended for consumption during the day. The product is not intended for children under 12 years of age and for pregnant and lactating women.

Liposomal preparations due to the structure of the molecule and its composition is best consumed within 3 months from the date of production.

After this period, the composition of the preparation does not deteriorate, but its bioavailability begins to decrease, which may result in a gradual decrease in its bioavailability.

Liposomal herbs are best used under the supervision of specialists (physician, phytotherapist or dietician) oriented in the problems of borreliosis and coinfection.

What is necessary:

A properly carried out diet,
healthy lifestyle,
properly detoxified body.

More information about the problem of tick-borne diseases can be obtained on our website: www.akademia-boreliozy.pl

on the blog of the phytotherapist Jan Oruba: https://fitoterapeuta.wordpress.com/
and the phytotherapist, Paweł Fekner – email: fitoterapeuta.pawel@interia.pl

Źródła badań dotyczące zastosowanych składników formuły / infografika w galerii produktu /:

Sources of research on the ingredients used in the formula / infographics in the product gallery /:

Dichroa febrifuga

  1. J Med Chem. 2002 Jun 6;45(12):2563-70.
    Potent antimalarial febrifugine analogues against the plasmodium malaria parasite.
    Kikuchi H1, Tasaka H, Hirai S, Takaya Y, Iwabuchi Y, Ooi H, Hatakeyama S, Kim HS, Wataya Y, Oshima Y.
    Studies in human malaria. XXV. Trial of febrifugine, an alkaloid obtained from Dichroa febrifuga lour., against the Chesson strain of Plasmodium vivax.
    COATNEY GR, COOPER WC, CULWELL WB, WHITE WC, IMBODEN CA Jr.
    J Natl Malar Soc. 1950 Jun;9(2):183-6. No abstract available.
    PMID: 15422372
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  2. Effect of Dichroa febrifuga L. on chloroquinsensible and chloroquinresistant malaria parasites.
    Zhao CX.
    J Tongji Med Univ. 1986;6(2):112-5. German. No abstract available.
    PMID: 3528514
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  3. Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis.
    Jain V, Yogavel M, Oshima Y, Kikuchi H, Touquet B, Hakimi MA, Sharma A.
    Structure. 2015 May 5;23(5):819-829. doi: 10.1016/j.str.2015.02.011. Epub 2015 Mar 26
    PMID: 25817387 Free Article
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  4. Dichroa Febrifuga and a Synthetic Hydrangea Alkaloid in Malaria.
    Chaudhuri RN, Dutta BN, Chakravarty RN.
    Ind Med Gaz. 1954 Nov;89(11):660-664. No abstract available.
    PMID: 29015682 Free PMC Article
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  5. East meets West: how China almost cured malaria.
    Burns WR.
    Endeavour. 2008 Sep;32(3):101-6. doi: 10.1016/j.endeavour.2008.07.001. Epub 2008 Aug 8.
    PMID: 18691761
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  6. Pharmacology of ch’ang shan (Dichroa febrifuga) a Chinese antimalarial herb.
    JANG CS, FU FY, et al.
    Nature. 1948 Mar 13;161(4089):400. No abstract available.
    PMID: 18916817
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  7. Effect of Dichroa febrifuga on Plasmodium berghei.
    Gopal H, Mohan V, Purushothaman KK.
    Indian J Pathol Microbiol. 1982 Oct;25(4):269-72. No abstract available.
    PMID: 6762348
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  8. Potent antimalarial febrifugine analogues against the plasmodium malaria parasite.
    Kikuchi H, Tasaka H, Hirai S, Takaya Y, Iwabuchi Y, Ooi H, Hatakeyama S, Kim HS, Wataya Y, Oshima Y.
    J Med Chem. 2002 Jun 6;45(12):2563-70.
    PMID: 12036365
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  9. Halofuginone – the multifaceted molecule.
    Pines M, Spector I.
    Molecules. 2015 Jan 5;20(1):573-94. doi: 10.3390/molecules20010573. Review.
    PMID: 25569515 Free Article
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  10. Febrifugine analogue compounds: synthesis and antimalarial evaluation.
    Zhu S, Chandrashekar G, Meng L, Robinson K, Chatterji D.
    Bioorg Med Chem. 2012 Jan 15;20(2):927-32. doi: 10.1016/j.bmc.2011.11.053. Epub 2011 Dec 2.
    PMID: 22182577 Free PMC Article
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  11. New type of febrifugine analogues, bearing a quinolizidine moiety, show potent antimalarial activity against Plasmodium malaria parasite.
    Takaya Y, Tasaka H, Chiba T, Uwai K, Tanitsu M, Kim HS, Wataya Y, Miura M, Takeshita M, Oshima Y.
    J Med Chem. 1999 Aug 12;42(16):3163-6.
    PMID: 10447961
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  12. Synthesis and evaluation of 4-quinazolinone compounds as potential antimalarial agents.
    Zhu S, Wang J, Chandrashekar G, Smith E, Liu X, Zhang Y.
    Eur J Med Chem. 2010 Sep;45(9):3864-9. doi: 10.1016/j.ejmech.2010.05.040. Epub 2010 May 24.
    PMID: 20538379 Free PMC Article
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  13. Exploration of a new type of antimalarial compounds based on febrifugine.
    Kikuchi H, Yamamoto K, Horoiwa S, Hirai S, Kasahara R, Hariguchi N, Matsumoto M, Oshima Y.
    J Med Chem. 2006 Jul 27;49(15):4698-706.
    PMID: 16854076
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  14. Potentiation by febrifugine of host defense in mice against Plasmodium berghei NK65.
    Murata K, Takano F, Fushiya S, Oshima Y.
    Biochem Pharmacol. 1999 Nov 15;58(10):1593-601.
    PMID: 10535750
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  15. Metabolites of febrifugine and its synthetic analogue by mouse liver S9 and their antimalarial activity against Plasmodium malaria parasite.
    Hirai S, Kikuchi H, Kim HS, Begum K, Wataya Y, Tasaka H, Miyazawa Y, Yamamoto K, Oshima Y.
    J Med Chem. 2003 Sep 25;46(20):4351-9.
    PMID: 13678413
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  16. ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase.
    Zhou H, Sun L, Yang XL, Schimmel P.
    Nature. 2013 Feb 7;494(7435):121-4. doi: 10.1038/nature11774. Epub 2012 Dec 23.
    PMID: 23263184 Free PMC Article
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  17. Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents.
    Zhu S, Zhang Q, Gudise C, Wei L, Smith E, Zeng Y.
    Bioorg Med Chem. 2009 Jul 1;17(13):4496-502. doi: 10.1016/j.bmc.2009.05.011. Epub 2009 May 9.
    PMID: 19467876 Free PMC Article
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  18. Comparison of antimalarial activity of the alkaloidal fraction of Hydrangea macrophylla var. Otaksa leaves with the hot-water extract in ICR mice infected with Plasmodium yoelii 17 XL.
    Ishih A, Miyase T, Terada M. Phytother Res. 2003 Jun;17(6):633-9.
    PMID: 12820231
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  19. Halofuginone attenuates intervertebral discs degeneration by suppressing collagen I production and inactivating TGFß and NF-?B pathway.
    Luo L, Gao Y, Yang C, Shao Z, Wu X, Li S, Xiong L, Chen C.
    Biomed Pharmacother. 2018 May;101:745-753. doi: 10.1016/j.biopha.2018.01.100. Epub 2018 Mar 22.
    PMID: 29524883
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Berberyna

J Vet Med Sci. 2005 Feb;67(2):223-7.
Antibabesial activity of protoberberine alkaloids and 20-hydroxyecdysone from Arcangelisia flava against Babesia gibsoni in culture.
Subeki1, Matsuura H, Takahashi K, Yamasaki M, Yamato O, Maede Y, Katakura K, Suzuki M, Trimurningsih, Chairul, Yoshihara T.

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Curcuma zedoaria

Anti-babesial compounds from Curcuma zedoaria.
Kasahara K, Nomura S, Subeki, Matsuura H, Yamasaki M, Yamato O, Maede Y, Katakura K, Suzuki M, Trimurningsih, Chairul, Yoshihara T.
Planta Med. 2005 May;71(5):482-4.

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Cryptolepis

  1. A review of the anticancer potential of the antimalarial herbal cryptolepis and its major alkaloid cryptolepine.
    Ansah C, Mensah KB.
    Ghana Med J. 2013 Sep;47(3):137-47. Review.
    PMID: 24391229 Free PMC Article
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  2. Improved traditional phytomedicines in current use for the clinical treatment of malaria.
    Willcox M.
    Planta Med. 2011 Apr;77(6):662-71. doi: 10.1055/s-0030-1250548. Epub 2011 Jan 3. Review.
    PMID: 21204042
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  3. The clinical efficacy of cryptolepis in the treatment of malaria.
    Tempesta MS.
    Ghana Med J. 2010 Mar;44(1):1-2. No abstract available.
    PMID: 21326982 Free PMC Article
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  4. Treatment of falciparum malaria with a tea-bag formulation of cryptolepis root.
    Ankrah NA.
    Ghana Med J. 2010 Mar;44(1):2. No abstract available.
    PMID: 21326983 Free PMC Article
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  5. Synergistic anti-malarial action of cryptolepine and artemisinins.
    Forkuo AD, Ansah C, Boadu KM, Boampong JN, Ameyaw EO, Gyan BA, Arku AT, Ofori MF.
    Malar J. 2016 Feb 16;15:89. doi: 10.1186/s12936-016-1137-5. Erratum in: Malar J. 2016;15(1):171.
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  6. Clinical efficacy of a tea-bag formulation of cryptolepis root in the treatment of acute uncomplicated falciparum malaria.
    Bugyei KA, Boye GL, Addy ME.
    Ghana Med J. 2010 Mar;44(1):3-9.
    PMID: 21326984 Free PMC Article
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  7. In vitro genotoxicity of the West African anti-malarial herbal Cryptolepis and its major alkaloid cryptolepine.
    Ansah C, Khan A, Gooderham NJ.
    Toxicology. 2005 Mar 1;208(1):141-7.
    PMID: 15664441
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  8. Recent developments in naturally derived antimalarials: cryptolepine analogues.
    Wright CW.
    J Pharm Pharmacol. 2007 Jun;59(6):899-904. Review.
    PMID: 17637183
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  9. Schistosomicidal and molluscicidal activities of aminoalkylamino substituted neo- and norneocryptolepine derivatives.
    El Bardicy S, El Sayed I, Yousif F, Van der Veken P, Haemers A, Augustyns K, Pieters L.
    Pharm Biol. 2012 Feb;50(2):134-40.
    PMID: 2233811
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  10. Cryptolepine derivative-6h inhibits liver fibrosis in TGF-ß1-induced HSC-T6 cells by targeting the Shh pathway.
    He YH, Li Z, Ni MM, Zhang XY, Li MF, Meng XM, Huang C, Li J.
    Can J Physiol Pharmacol. 2016 Sep;94(9):987-95. doi: 10.1139/cjpp-2016-0157. Epub 2016 Apr 28.
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  11. Antimalarial activity of 20 crude extracts from nine African medicinal plants used in Kinshasa, Congo.
    Tona L, Ngimbi NP, Tsakala M, Mesia K, Cimanga K, Apers S, De Bruyne T, Pieters L, Totté J, Vlietinck AJ.
    J Ethnopharmacol. 1999 Dec 15;68(1-3):193-203.
    PMID: 1062487
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  12. Phytochemical and Pharmacological Review of Cryptolepis (Lindl.) Schlechter.
    Osafo N, Mensah KB, Yeboah OK.
    Adv Pharmacol Sci. 2017;2017:3026370. doi: 10.1155/2017/3026370. Epub 2017 Oct 15. Review.
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  13. In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine.
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    Malar J. 2017 Dec 28;16(1):496. doi: 10.1186/s12936-017-2142-z.
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Propolis

  1. In vitro evaluation of Portuguese propolis and floral sources for antiprotozoal, antibacterial and antifungal activity.
    Falcao SI, Vale N, Cos P, Gomes P, Freire C, Maes L, Vilas-Boas M.
    Phytother Res. 2014 Mar;28(3):437-43. doi: 10.1002/ptr.5013. Epub 2013 May 31.
    PMID: 23722631
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  2. In vitro antimicrobial assessment of Cuban propolis extracts.
    Monzote L, Cuesta-Rubio O, Campo Fernandez M, Márquez Hernandez I, Fraga J, Pérez K, Kerstens M, Maes L, Cos P.
    Mem Inst Oswaldo Cruz. 2012 Dec;107(8):978-84.
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  3. Chemical and Antimicrobial Profiling of Propolis from Different Regions within Libya.
    Siheri W, Zhang T, Ebiloma GU, Biddau M, Woods N, Hussain MY, Clements CJ, Fearnley J, Ebel RE, Paget T, Muller S, Carter KC, Ferro VA, De Koning HP, Watson DG.
    PLoS One. 2016 May 19;11(5):e0155355. doi: 10.1371/journal.pone.0155355. eCollection 2016.
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  4. Anti-Plasmodial Assessment of Four Different Iranian Propolis Extracts.
    Afrouzan H, Zakeri S, Abouie Mehrizi A, Molasalehi S, Tahghighi A, Shokrgozar MA, Es-Haghi A, Dinparast Djadid N.
    Arch Iran Med. 2017 May;20(5):270-281. doi: 0172005/AIM.004.
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  5. In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae).
    da Silva Filho AA, Resende DO, Fukui MJ, Santos FF, Pauletti PM, Cunha WR, Silva ML, Gregório LE, Bastos JK, Nanayakkara NP.
    Fitoterapia. 2009 Dec;80(8):478-82. doi: 10.1016/j.fitote.2009.06.007. Epub 2009 Jun 18.
    PMID: 19540316
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  6. In vivo assessment of the antimalarial and spleen-protective activities of the Saudi propolis methanolic extract.
    AlGabbani Q, Mansour L, Elnakady YA, Al-Quraishy S, Alomar S, Al-Shaebi EM, Abdel-Baki AS.
    Parasitol Res. 2017 Feb;116(2):539-547. doi: 10.1007/s00436-016-5318-5. Epub 2016 Nov 7.
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Olejek kurkumowy

AAPS PharmSciTech. 2018 Feb;19(2):551-564. doi: 10.1208/s12249-017-0854-6. Epub 2017 Sep 5.
Optimization of Curcuma Oil/Quinine-Loaded Nanocapsules for Malaria Treatment.

Gomes GS1, Maciel TR2, Piegas EM1, Michels LR2, Colomé LM1,2, Freddo RJ1, Ávila DS3, Gundel A4, Haas SE5,6.

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Olejek z trawy cytrynowej

  1. Parasitol Int. 2010 Jun;59(2):278-82. doi: 10.1016/j.parint.2010.02.006. Epub 2010 Feb 21.
    Inhibitory effect of terpene nerolidol on the growth of Babesia parasites.
    AbouLaila M1, Sivakumar T, Yokoyama N, Igarashi I.
  2. Activity of Ocimum basilicum, Ocimum canum, and Cymbopogon citratus essential oils against Plasmodium falciparum and mature-stage larvae of Anopheles funestus s.s.
    Akono Ntonga P, Baldovini N, Mouray E, Mambu L, Belong P, Grellier P.
    Parasite. 2014;21:33. doi: 10.1051/parasite/2014033. Epub 2014 Jul 7.
    PMID: 24995776 Free PMC Article
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  3. Chemical composition, cytotoxicity and in vitro antitrypanosomal and antiplasmodial activity of the essential oils of four Cymbopogon species from Benin.
    Kpoviessi S, Bero J, Agbani P, Gbaguidi F, Kpadonou-Kpoviessi B, Sinsin B, Accrombessi G, Frédérich M, Moudachirou M, Quetin-Leclercq J.
    J Ethnopharmacol. 2014;151(1):652-9. doi: 10.1016/j.jep.2013.11.027. Epub 2013 Nov 21.
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  4. Exploring the antimalarial potential of whole Cymbopogon citratus plant therapy.
    Chukwuocha UM, Fernández-Rivera O, Legorreta-Herrera M.
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  5. In vivo antimalarial activity of essential oils from Cymbopogon citratus and Ocimum gratissimum on mice infected with Plasmodium berghei.
    Tchoumbougnang F, Zollo PH, Dagne E, Mekonnen Y.
    Planta Med. 2005 Jan;71(1):20-3.
    PMID: 1567836
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  6. Anti-malarial activity of a polyherbal product (Nefang) during early and established Plasmodium infection in rodent models.
    Tarkang PA, Okalebo FA, Ayong LS, Agbor GA, Guantai AN.
    Malar J. 2014 Nov 25;13:456. doi: 10.1186/1475-2875-13-456.
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  7. Prophylactic effect of multi-herbal extract ‚Agbo-Iba’ on malaria induced in mice.
    Nwabuisi C.
    East Afr Med J. 2002 Jul;79(7):343-6.
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  8. In vitro antiplasmodial activities and synergistic combinations of differential solvent extracts of the polyherbal product, Nefang.
    Arrey Tarkang P, Franzoi KD, Lee S, Lee E, Vivarelli D, Freitas-Junior L, Liuzzi M, Nolé T, Ayong LS, Agbor GA, Okalebo FA, Guantai AN.
    Biomed Res Int. 2014;2014:835013. doi: 10.1155/2014/835013. Epub 2014 Apr 27.
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  9. Efficacy of Cymbopogon giganteus and Enantia chrantha against chloroquine resistant Plasmodium yoelii nigeriensis.
    Kimbi HK, Fagbenro-Beyioku AF.
    East Afr Med J. 1996 Oct;73(10):636-7.
    PMID: 8997841
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  10. Mitotic effects of the aqueous leaf extract of Cymbopogon citratus in Allium cepa root tips.
    Williams GO, Omoh LE.
    Cytobios. 1996;87(350):161-8.
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  11. Medicinal plants used by the people of Nsukka Local Government Area, south-eastern Nigeria for the treatment of malaria: An ethnobotanical survey.
    Odoh UE, Uzor PF, Eze CL, Akunne TC, Onyegbulam CM, Osadebe PO.
    J Ethnopharmacol. 2018 May 23;218:1-15. doi: 10.1016/j.jep.2018.02.034.
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Akono Ntonga, Patrick, Nicolas Baldovini, Elisabeth Mouray, Lengo Mambu, Philippe Belong, and Philippe Grellier. “Activity of Ocimum Basilicum, Ocimum Canum, and Cymbopogon Citratus Essential Oils against Plasmodium Falciparum and Mature-Stage Larvae of Anopheles Funestus S.s.” Parasite

(Paris, France) 21 (2014): 33. doi:10.1051/parasite/2014033. http://www.ncbi.nlm.nih.gov/pubmed/24995776

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Olejek niaouli ( Melaleuca viridiflora)

J Med Food. 2011 Nov;14(11):1383-8. doi: 10.1089/jmf.2010.0168. Epub 2011 Apr 10.

Chemical study and antimalarial, antioxidant, and anticancer activities of Melaleuca armillaris (Sol Ex Gateau) Sm essential oil.

Chabir N1, Romdhane M, Valentin A, Moukarzel B, Marzoug HN, Brahim NB, Mars M, Bouajila J.

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Olejek ylang ylang

Tan, Loh Teng Hern, Learn Han Lee, Wai Fong Yin, Chim Kei Chan, Habsah Abdul Kadir, Kok Gan Chan, and Bey Hing Goh. “Traditional Uses, Phytochemistry, and Bioactivities of Cananga Odorata (Ylang-Ylang).” Evidence-Based Complementary and Alternative Medicine

: eCAM 2015 (2015). doi:10.1155/2015/896314. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534619/